InnovaCoat® GOLD-Carboxyl nanoparticles are coated gold nanoparticles functionalized with carboxyl groups that allow the covalent conjugation of antibodies, using the water soluble carbodiimide crosslinker EDC.
The product enables the generation of highly stable covalent gold-antibody conjugates at R&D and manufacturing scales.
Unlike traditional EDC/NHS coupling used to activate carboxyl groups, InnovaCoat® GOLD-Carboxyl nanoparticles are optimized for single step EDC covalent coupling without signs of aggregation. This eliminates the need for EDC/NHS pre-activation and washing steps associated with traditional conjugations.
This process is also significantly faster than standard methods, with conjugates ready to use in less than 35 minutes.
InnovaCoat® GOLD carboxyl nanoparticles have a narrow size distribution, a uniform spherical shape and high batch-to-batch consistency.
Mean Diameter 36-44nm
Composition: 40nm carboxyl-gold 40 OD carboxyl gold nanoparticles web
Adsorption max: 530nm
Particles per ml: 36 x 1011
Volume: 1ml and 5ml
Buffer: 10mM EPPS pH 8.5
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